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Coronavirus Thread (Off Topic, Politics) (10 Viewers)

  • Thread starter BackRoomRummermill
  • Start date Feb 23, 2020
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baldy

Well-Known Member
  • Aug 23, 2023
  • #58,171
I wouldn’t take any more covid jabs if they were on offer either tbh - I’ve been jabbed 3 times…that’s more than enough
 
W

wingy

Well-Known Member
  • Aug 23, 2023
  • #58,172
baldy said:
I wouldn’t take any more covid jabs if they were on offer either tbh - I’ve been jabbed 3 times…that’s more than enough
Click to expand...
This is what I don't get, I've also had 3 and the 3rd one was biontech I think,and that changes something in the gene's or cells so what's the need?
 
Reactions: bezzer

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,173
baldy said:
I wouldn’t take any more covid jabs if they were on offer either tbh - I’ve been jabbed 3 times…that’s more than enough
Click to expand...

And are you the same for flu? Is it the seasonality of it? Or just that it’s COVID?
 
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,174
wingy said:
This is what I don't get, I've also had 3 and the 3rd one was biontech I think,and that changes something in the gene's or cells so what's the need?
Click to expand...
Because over time the mutations in the virus will help it escape any remaining immunity you have to whatever you were vaccinated against.
 
Reactions: wingy

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,175
wingy said:
This is what I don't get, I've also had 3 and the 3rd one was biontech I think,and that changes something in the gene's or cells so what's the need?
Click to expand...

mRNA vaccines don’t change anything in your DNA or cells. Like other vaccines it’s just a method to provoke an immune response. No vaccine is in your system after a few weeks, the entire point is to prime your immune system, not to augment it.

This is a good explainer of mRNA vaccines: Will an mRNA vaccine alter my DNA?
 
Reactions: Sick Boy, hill83, Sky Blue Pete and 2 others

Ian1779

Well-Known Member
  • Aug 23, 2023
  • #58,176
SkyBlueCharlie9 said:
Couple of people I know here in Kent suggest they have it. Just checked out Government website which suggests slight increase since July in cases and hospitalisations but not deaths. To be expected there will be peaks and troughs but let's hope Richie has a plan up his sleeve just in case.
Click to expand...
He’s got a plan for himself…. Acquire a stake in a pharmaceutical company and then shortly declare that boosters can be purchased…..
 
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,177
shmmeee said:
mRNA vaccines don’t change anything in your DNA or cells. Like other vaccines it’s just a method to provoke an immune response. No vaccine is in your system after a few weeks, the entire point is to prime your immune system, not to augment it.

This is a good explainer of mRNA vaccines: Will an mRNA vaccine alter my DNA?
Click to expand...
Indeed, but the memory cells are what remain from the initial vaccination and provide the lasting immunity. Though we don’t know in this instance how long they hang around for.
 
Reactions: Sky Blue Pete

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,178
Brighton Sky Blue said:
Indeed, but the memory cells are what remain from the initial vaccination and provide the lasting immunity. Though we don’t know in this instance how long they hang around for.
Click to expand...

Sorry yeah, was more focusing on the belief your genes were changed.

So is the specific issue with COVID that any immunity wanes or that the virus evolves like flu and needs a different response? Like am I still OK against whatever the fuck was before Omicron or what? TBH I’ve not paid a blind bit of attention for ages.
 
Reactions: Saddlebrains, Brighton Sky Blue and Sky Blue Pete
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,179
shmmeee said:
Sorry yeah, was more focusing on the belief your genes were changed.

So is the specific issue with COVID that any immunity wanes or that the virus evolves like flu and needs a different response? Like am I still OK against whatever the fuck was before Omicron or what? TBH I’ve not paid a blind bit of attention for ages.
Click to expand...
The virus is continuously mutating to be more infectious and/or resistant to immunity (some mutations are more advantageous for one than the other) so that it can keep reproducing. I don't know how quickly COVID does it compared to flu, but that one and the common cold will mutate every year and so we'll keep catching them till we die. For the flu we look to the southern hemisphere to see what strains are becoming dominant during their winters so we can prepare the next round of vaccines. It's kind of a very well educated guess.

With COVID we've got tracking all over the world to identify emerging strains more quickly and thus keep on top of preparing new vaccines. But it'll be pretty much a round the year task from hereon.
 
Reactions: shmmeee

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,180
Brighton Sky Blue said:
The virus is continuously mutating to be more infectious and/or resistant to immunity (some mutations are more advantageous for one than the other) so that it can keep reproducing. I don't know how quickly COVID does it compared to flu, but that one and the common cold will mutate every year and so we'll keep catching them till we die. For the flu we look to the southern hemisphere to see what strains are becoming dominant during their winters so we can prepare the next round of vaccines. It's kind of a very well educated guess.

With COVID we've got tracking all over the world to identify emerging strains more quickly and thus keep on top of preparing new vaccines. But it'll be pretty much a round the year task from hereon.
Click to expand...

Yeah that was my understanding: it was more like flu than say the measles vaccine or whatever. Which brings me back to the original question I guess: why take flu and not COVID?
 
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,181
shmmeee said:
Yeah that was my understanding: it was more like flu than say the measles vaccine or whatever. Which brings me back to the original question I guess: why take flu and not COVID?
Click to expand...
I'd take both if I had the choice and would recommend anyone else to do the same if they're in an at-risk category.
 
Reactions: Deleted member 9744 and shmmeee

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,182
Brighton Sky Blue said:
I'd take both if I had the choice and would recommend anyone else to do the same if they're in an at-risk category.
Click to expand...

I shall continue my time honoured tradition of doing whatever the NHS tells me and in the meantime killing anything near my body with a mix of tobacco strong coffee and anxiety.
 
Reactions: Sky Blue Pete and OffenhamSkyBlue
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,183
shmmeee said:
I shall continue my time honoured tradition of doing whatever the NHS tells me and in the meantime killing anything near my body with a mix of tobacco strong coffee and anxiety.
Click to expand...
Fast food for me. I reckon I've had enough preservatives, sweeteners and E-numbers to kill off any virus
 

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,184
Brighton Sky Blue said:
Fast food for me. I reckon I've had enough preservatives, sweeteners and E-numbers to kill off any virus
Click to expand...

How could I forget!? You’ve seen that meme about the happy meal that looks identical a decade after it’s bought? That’s basically my insides. Should be enough to see me through to nanobots.
 
Reactions: Sky Blue Pete and Brighton Sky Blue

baldy

Well-Known Member
  • Aug 23, 2023
  • #58,185
shmmeee said:
And are you the same for flu? Is it the seasonality of it? Or just that it’s COVID?
Click to expand...

I‘ve never had a flu jab & never will
 

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,186
baldy said:
I‘ve never had a flu jab & never will
Click to expand...

How come?
 

baldy

Well-Known Member
  • Aug 23, 2023
  • #58,187
shmmeee said:
How come?
Click to expand...

Mixture of personal choice & just the fact I’m healthy enough to overcome flu as I’m not in any at-risk category
 
Reactions: shmmeee

Sky_Blue_Dreamer

Well-Known Member
  • Aug 23, 2023
  • #58,188
baldy said:
Mixture of personal choice & just the fact I’m healthy enough to overcome flu as I’m not in any at-risk category
Click to expand...
That's got serious start of a horror movie vibes.
 

shmmeee

Well-Known Member
  • Aug 23, 2023
  • #58,189
Sky_Blue_Dreamer said:
That's got serious start of a horror movie vibes.
Click to expand...

Man’s healthy enough, why would he want to get any healthier?
 
B

Brighton Sky Blue

Well-Known Member
  • Aug 23, 2023
  • #58,190
shmmeee said:
Man’s healthy enough, why would he want to get any healthier?
Click to expand...
Man’s not hot



For now
 
O

OffenhamSkyBlue

Well-Known Member
  • Aug 24, 2023
  • #58,191
Brighton Sky Blue said:
The virus is continuously mutating to be more infectious and/or resistant to immunity (some mutations are more advantageous for one than the other) so that it can keep reproducing. I don't know how quickly COVID does it compared to flu, but that one and the common cold will mutate every year and so we'll keep catching them till we die. For the flu we look to the southern hemisphere to see what strains are becoming dominant during their winters so we can prepare the next round of vaccines. It's kind of a very well educated guess.

With COVID we've got tracking all over the world to identify emerging strains more quickly and thus keep on top of preparing new vaccines. But it'll be pretty much a round the year task from hereon.
Click to expand...
Just a couple of comments on your excellent post ...

1. Viruses will be mutating all the time, and some mutations will enhance its activity while others will reduce it. Those activities include the ability to bind to its target cells, which is in general an indicator of how fast the virus is taken up by the cell and starts replicating, the point at which it causes the disease. These (for Covid) are usually mutations in the Spike coat protein which we heard so much about when a new variant was doing the rounds. Other mutations may affect the actual ability to cause the disease itself. The hope was that a mutant would emerge which spread faster but had lost the ability to cause severe disease. This may have become fixed in the population and out-competed the more severe strains.

2. The overall mutation rate of Covid has been shown to be about 25 times LOWER than Influenza A virus due to a proof-reading mechanism in the proteins which replicate the viral genome.

And to reiterate, no mRNA molecule (vaccine or otherwise) can directly alter the genome of any cell it enters. Its purpose is to be translated to produce the Spike protein which then gets recognised by the cells (and other non-cellular components) of the immune system to generate an immune response. This is very long-lived, although does reduce over time, hence the need for booster vaccines.
 
Reactions: Brighton Sky Blue and wingy

Sky Blue Pete

Well-Known Member
  • Aug 24, 2023
  • #58,192
baldy said:
Mixture of personal choice & just the fact I’m healthy enough to overcome flu as I’m not in any at-risk category
Click to expand...
Are you not over 50
 
Reactions: Sick Boy

skybluetony176

Well-Known Member
  • Aug 24, 2023
  • #58,193
I don’t get the resistance to getting the vaccine boosters. You’re basically saying I’m going to rely on getting immunity from catching it on a regular basis, think I read you have to catch it three times a year to gain the same immunity as the booster. If that’s right why not just get the booster in the first place?
 

Saddlebrains

Well-Known Member
  • Aug 24, 2023
  • #58,194
skybluetony176 said:
I don’t get the resistance to getting the vaccine boosters. You’re basically saying I’m going to rely on getting immunity from catching it on a regular basis, think I read you have to catch it three times a year to gain the same immunity as the booster. If that’s right why not just get the booster in the first place?
Click to expand...


I just cant buy into any 'booster' thats been needed to be stuck into people 6 or 7 times in 3 years tbh
 

chiefdave

Well-Known Member
  • Aug 24, 2023
  • #58,195
Saddlebrains said:
I just cant buy into any 'booster' thats been needed to be stuck into people 6 or 7 times in 3 years tbh
Click to expand...
How have you been offered so many? I’m classed as vulnerable and have had every one offered and I’ve had 4. The initial two and then winter boosters the last 2 winters in line with the flu vaccination program we’ve been running for years.

There was a spring booster for the most vulnerable this year but I’m pretty sure that’s the only one so far I haven’t been offered
 

Nick

Administrator
  • Aug 24, 2023
  • #58,196
Am I the only one who's never had a flu jab?
 

Saddlebrains

Well-Known Member
  • Aug 24, 2023
  • #58,197
chiefdave said:
How have you been offered so many? I’m classed as vulnerable and have had every one offered and I’ve had 4. The initial two and then winter boosters the last 2 winters in line with the flu vaccination program we’ve been running for years.

There was a spring booster for the most vulnerable this year but I’m pretty sure that’s the only one so far I haven’t been offered
Click to expand...


I was exaggerating tbf, was offered boosters after the initial 2 but im not doing it. The initial 2 and a natural infection of it at 33 id like to think my immune system is good enough to cope
 
S

SBT

Well-Known Member
  • Aug 24, 2023
  • #58,198
Saddlebrains said:
I was exaggerating tbf, was offered boosters after the initial 2 but im not doing it. The initial 2 and a natural infection of it at 33 id like to think my immune system is good enough to cope
Click to expand...
So why do you feel confident about dealing with Covid on your own without a booster, but not the flu?
 

Saddlebrains

Well-Known Member
  • Aug 24, 2023
  • #58,199
SBT said:
So why do you feel confident about dealing with Covid on your own without a booster, but not the flu?
Click to expand...


Because ive had flu and its horrendous, couldnt get out of bed for days.

Had covid twice and i genuinely felt fine apart from a bit tired and couldnt eat sauce
 

clint van damme

Well-Known Member
  • Aug 24, 2023
  • #58,200
Nick said:
Am I the only one who's never had a flu jab?
Click to expand...

How old are you?
I've only started having them in the last year or two. Think they should of offered me them earlier but saw what a fine figure of health I was and didn't bother.
 
Reactions: Nick and Grendel

Grendel

Well-Known Member
  • Aug 24, 2023
  • #58,201
clint van damme said:
How old are you?
I've only started having them in the last year or two. Think they should of offered me them earlier but saw what a fine figure of health I was and didn't bother.
Click to expand...
 
Reactions: clint van damme

baldy

Well-Known Member
  • Aug 24, 2023
  • #58,202
Nick said:
Am I the only one who's never had a flu jab?
Click to expand...

Nope - same here
 

baldy

Well-Known Member
  • Aug 24, 2023
  • #58,203
Sky Blue Pete said:
Are you not over 50
Click to expand...

Cheeky fucker - I’m only 47
 
Reactions: Sky Blue Pete

Sick Boy

Super Moderator
  • Aug 24, 2023
  • #58,204
Nick said:
Am I the only one who's never had a flu jab?
Click to expand...
I’m later 30s and never had one.
 

shmmeee

Well-Known Member
  • Aug 24, 2023
  • #58,205
Had one when I was a teacher. The missus gets one cos she works in the NHS
 
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